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06344


Physik (Master) Sommersemester 2010
06344 Theoretische Biophysik [V]
   
Dozent Goychuk I.
Dauer 4 SWS
Studiensemester 0
Schein Ja (Mündl.Prüfung; 8 LP)
Beginn 21.04.10
Inhalt
  1. Cell structure and organization
  2. Molecular forces in biological structures. Molecular dynamics and visualization
  3. Conformational transitions in proteins
  4. Biochemical reactions: macroscopic enzyme kinetics and stochastic effects
  5. Gene-protein regulatory circuits, genetic switches and oscillators
  6. Transmembrane transport: ion channels, pumps, and transporters
  7. Excitable membranes: Hodgkin-Huxley model and bottom-up approach
  8. Molecular motors as macromolecular Brownian machines and biochemical cycle kinetics
Begleitend 06345
Vorkenntnisse Mechanik, Elektrodynamik, Statistische Physik

Literatur
  1. P. Nelson, Biological Physics: Energy, Information, Life (Freeman, New York, 2004).
  2. M. B. Jackson, Molecular and Cellular Biophysics (Cambridge University Press, 2006)
  3. J. Keener and J. Sneyd, Mathematical Physiology (Springer, New York, 2001).
  4. T. L. Hill, Free Energy Transduction and Biochemical Cycle Kinetics (Dover Publications, 2004)
  5. R. Nossal and H. Lecar, Molecular and Cell Biophysics (Addison-Wesley, Redwood City, 1991)
  6. B. Alberts, et al. Molecular Biology of the Cell, 4th ed. (Garland Science, 2002)
  7. P. Atkins and J. de Paula, Atkin's Physical Chemistry, 8th ed. (Oxford University Press, Oxford, 2006)