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06365


Physik Lehramt Gymnasium Wintersemester 2007/2008
06365 Molecular and Cellular Biophysics: Basic Principles and Theoretical Modeling [V]
   
Dozent Goychuk I.
Dauer 4 SWS
Studiensemester 7
Schein Nein
Termin Di, 12:15 - 13:45, 2004/HZ
Do, 12:15 - 13:45, 1003/HZ
Beginn 16.10.2007
Inhalt
  • Cell organization and molecules of life: structural properties and importance of dynamics
  • Dynamical and statistical (entropic) forces in biological media. Molecular dynamics and its visualization
  • Biochemical reactions: enzyme kinetics, stochastic (small number) effects, gene-protein circuits, genetical switches and oscillators; dynamical and stochastic modeling
  • Membrane transport on nanoscale: ion channels and transporters
  • Excitable membranes: Hodgkin-Huxley model and beyond
  • Molecular motors as macromolecular machines
  • Experiments with single molecules and their theoretical foundation
Vorkenntnisse Statistische Physik, Elektrodynamik
Literatur
  1. P. Nelson, Biological Physics: Energy, Information, Life (WH Freeman, New York, 2004)
  2. M.B. Jackson, Molecular and Cellular Biophysics (Cambridge University Press, Cambridge, 2006)
  3. R.J. Nossal and H. Lecar, Molecular and Cell Biophysics (Addison-Wesley, Redwood City, 1991)
  4. J. Keener and J. Sneyd, Mathematical Physiology (Springer, New York, 2001)
  5. M.V. Volkenstein, Biophysics (Nauka, Moscow, 1981; AIP Translation, 1995 -- a famous Russian textbook)
  6. B. Alberts et al., Molecular Biology of the Cell, 4th ed. (Garland Science, 2002)
  7. V.A. Parsegian, Van der Waals Forces: a Handbook for Biologists, Chemists, Engineers, and Physicists (Cambridge University Press, Cambridge, 2006)