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Dr. Christoph Westerhausen


Dr. Christoph Westerhausen

Group Leader Biophysics Group

E-Mail: christoph.westerhausen@physik.uni-augsburg.de
Telefon: +49 821 598 - 3311
Fax: +49 821 598 - 3225
Raum: 335
Hausanschrift: Universitätsstr. 1
86159 Augsburg, Germany


Announcements

>> Bachelorkandidaten/innen gesucht zur Mitarbeit bei der Entwicklung antibakterieller abriebarmer Implantate!

Interesse? Dann melden Sie sich bei Sascha Buchegger oder Christoph Westerhausen<<

>> Visiting the nuclear power plant in Gundremmingen - Very impressive machinery and technology!

>> Research: Thanks to the organizing team of the fantastic CeNS Workshop 2017 "Design and Control of NanoSystems" in Venice! (https://www.cens.de/calendar/workshops-events/venice-2017/)

>> 1. Biophysics Workshop SDR  - Thank you for your great contributions!

workshop20170807

>> Research: Sascha´s paper "Multilayer diamond-like amorphous carbon coatings produced by ion irradiation of polymer films" was just recently published in Surface and Coatings Technology!

>> Visiting a hip endoprothesis operation at the Zentralklinikum Augsburg - A very interesting day and so many ideas for collaborations!

Klinik-OP-Besuch

>> Research: Anna, Andrej and Manuel presented their cool results on the European Biophysics Congress in Edinburgh:

Anna Jötten, Poster: "Red blood cell aggregates in malaria - the role of flow"

Andrej Kamenac, Poster: " Enzyme Activity at Lipid Membranes – Correlation of Activity and Membrane State"

Manuel Brugger, Talk: "Orchestrating cells on a chip employing standing surface acoustic waves towards neural networks".

EBSA2017-Brugger

>> Research: Thanks to the organizing team of the "sawsome" Summer School "Physics and applications of GHz vibrations" in Cargése (http://summerschool.sawtrain.eu/about.html)!

SAWTrain SummerSchool

>> Outreach: Sixuan´s project as part of the ITN SAWTrain is featured by the "Forschungsbeilage" of the Augsburger Allgemeine (http://www.youblisher.com/p/1850399-/)!

>> Research: Mario´s paper "Influence of neighboring adherent cells on laminar flow induced shear stress in vitro - a systematic study" has just been accepted published by Biomicrofluidics and will appeared in the March April issue!
http://scitation.aip.org/content/aip/journal/bmf/11/2/10.1063/1.4979295

>> Melanie Stamp graduated on March 28th - Congratulations!

>> Research: Melanie´s paper "Exploring the limits of cell adhesion under shear stress within physiological conditions and beyond on a chip" studying the role of pH, temperature and substrate roughness under flow, appeared today in Diagnostics 2016, 6(4),38;                                http://www.mdpi.com/2075-4418/6/4/38/html

>> Teaching: New lecture “Physics of cells” (Physics, Masters level) started October 2016

>> Research: Find our latest article on “Controllable Acoustic Mixing of Fluids in Microchannels for the Fabrication of Therapeutic Nanoparticles” based on Lukas work that appeared in Micromachines 2016, 7(9), 150; http://www.mdpi.com/2072-666X/7/9/150/html

>> Research: Sascha´s paper “Antibacterial metal ion release from diamond-like carbon modified surfaces for novel multifunctional implant materials” is the cover and appears in JMR 31(17), September 14, 2016.  

>> Research: Out now: “Acoustotaxis - In vitro stimulation in a wound healing assay employing surface acoustic waves” Biomaterials Science, DOI: 10.1039/C6BM00125D
Get article here!

>> Research: We proudly present... ARAM - an awesome tool for Malaria Research and Microscopy!
- Download publication here!
- Download ARAM here!

 

Overview Westerhausen Group

 

Research Interests

Cell manipulation and stimulation
  • Acoustical stimulation of cell proliferation and migration
  • Cell adhesion under flow
  • Neural networks
Thermodynamics of membranes
  • Correlation of membrane state and enzyme activity
  • Nanoparticle uptake in cells and lipid vesicles

Cell-Cell interaction in Malaria

  • Dynamics of red blood cell aggregates (rosettes)

New Biomaterials

  • Wear resist and antibacterial diamond-like carbon surface modifications for implants

Acoustic Waves in fluidics

  • Fast mixing at low Reynolds numbers for creation of therapeutic nanoparticles

Acoustophotocatalysis

  • Employing SAW in heterogeneous catalysis

 

Selected publications

  • S. Buchegger, N. Schuster, B. Stritzker, A. Wixforth, and C. Westerhausen, “Multilayer diamond-like amorphous carbon coatings produced by ion irradiation of polymer films,” Surf. Coatings Technol., vol. 327, pp. 42–47, Oct. 2017.
  • M. Djukelic, A. Wixforth, and C. Westerhausen, Influence of neighboring adherent cells on laminar flow induced shear stress in vitro - a systematic study,” Biomicrofluidics, Apr. 2017.
  • M. E. M. Stamp, A. M. Jötten, P. W. Kudella, D. Breyer, F. G. Strobl, T. M. Geislinger, A. Wixforth, and C. Westerhausen, “Exploring the limits of cell adhesion under shear stress within physiological conditions and beyond on a chip,” Diagnostics, 6(4), 38; Oct. 2016.
  • C. Westerhausen, L. Schnitzler, D. Wendel, R. Krzysztoń, U. Lächelt, E. Wagner, J. Rädler, and A. Wixforth, “Controllable Acoustic Mixing of Fluids in Microchannels for the Fabrication of Therapeutic Nanoparticles,” Micromachines, vol. 7, no. 9, p. 150, Sep. 2016.

  • S. Buchegger, C. Vogel, R. Herrmann, B. Stritzker, A. Wixforth, and C. Westerhausen, “Antibacterial metal ion release from diamond-like carbon modified surfaces for novel multifunctional implant materials,” J. Mater. Res., vol. 31, no. 17, Sep. 2016.

  • M. E. M. Stamp*, M. S. Brugger*, A. Wixforth, and C. Westerhausen, “Acoustotaxis – in vitro stimulation in a wound healing assay employing surface acoustic waves,” Biomater. Sci., vol. 4, no. 7, pp. 1092–1099, May 2016 (* equally contributing).

  • P. W. Kudella, K. Moll, M. Wahlgren, A. Wixforth, and C. Westerhausen, “ARAM: an automated image analysis software to determine rosetting parameters and parasitaemia in Plasmodium samples,” Malar. J., vol. 15, no. 1, p. 223, Apr. 2016.
  • U. Ratzel, L. Herrmann, C. Westerhausen, O. Bayer, K.-G. Krapf, M. Hoffmann, J. Blaul, and C. Mehnert, “Tieffrequente Geräusche (inkl. Infraschall) von Windkraftanlagen und anderen Quellen,” in DAGA 2016, 2016.
  • M. E. M. Stamp, M. Brugger, A. Wixforth, and C. Westerhausen, “Manipulation of Cell Proliferation and Migration Employing Surface Acoustic Waves and Hydrophobic/Hydrophilic Structured Substrates,” Biophys. J., vol. 110, no. 3, p. 169a, Feb. 2016.
  • M. Stamp, A. M. Jötten, D. Breyer, M. Djukelic, F. Strobl, P. Kudella, A. Hartmann, A. Wixforth, and C. Westerhausen, “A novel tool for in vitro correlation of cell adhesion behavior and local shear flow,” Eur. Biophys. J., vol. 44, no. S1, p. 227, Jul. 2015.
  • M. S. Brugger, M. Stamp, A. Wixforth, and C. Westerhausen, “Acoustotaxis –Manipulation of cell proliferation and migration using surface acoustic waves,” in Eur. Biophys. J., vol. 44, no. S1, p. S222, Jul. 2015
  • F. G. Strobl, F. Seitz, C. Westerhausen, A. Reller, A. a Torrano, C. Bräuchle, A. Wixforth, and M. F. Schneider, “Intake of silica nanoparticles by giant lipid vesicles: influence of particle size and thermodynamic membrane state,” Beilstein J. Nanotechnol., vol. 5, pp. 2468–2478, Dec. 2014.
  • U. Ratzel, O. Bayer, P. Brachat, L. Herrmann, K.-G. Krapf, and C. Westerhausen, “Tieffrequente Geräusche und Infraschall von Windkraftanlagen und anderen Quellen,” 2014. [Online]. Available: http://www.lubw.baden-wuerttemberg.de/servlet/is/223895/.
  • C. Westerhausen, F. G. Strobl, R. Herrmann, A. T. Bauer, S. W. Schneider, A. Reller, A. Wixforth, and M. F. Schneider, “Chemical and Mechanical Impact of Silica Nanoparticles on the Phase Transition Behavior of Phospholipid Membranes in Theory and Experiment,” Biophys. J., vol. 102, no. 5, pp. 1032–1038, Mar. 2012.
  • A. T. Bauer, E. A. Strozyk, C. Gorzelanny, C. Westerhausen, A. Desch, M. F. Schneider, and S. W. Schneider, “Cytotoxicity of silica nanoparticles through exocytosis of von Willebrand factor and necrotic cell death in primary human endothelial cells,” Biomaterials, vol. 32, no. 33, pp. 8385–8393, Nov. 2011.
  • S. Niland, C. Westerhausen, S. W. Schneider, B. Eckes, M. F. Schneider, and J. a. Eble, “Biofunctionalization of a generic collagenous triple helix with the α1 integrin binding site allows molecular force measurements,” Int. J. Biochem. Cell Biol., vol. 43, no. 5, pp. 721–731, May 2011.
  • C. Westerhausen, “On the role of soft interfaces for the understanding of blood clotting,” Dissertation, University of Augsburg, 2012. Available: http://opus.bibliothek.uni-augsburg.de/opus4/files/1931/Dissertation_Westerhausen_Christoph.pdf

 

Short CV

since 2014:
Research assistant, Experimentalphysik 1, University of Augsburg

2012 – 2015:
Project manager at Wölfel Beratende Ingenieure, Würzburg

2012:
Dissertation „On the role of soft interfaces for the understanding of blood clotting”

2011:
6-month research period at Boston University

2009 – 2012:
University of Augsburg & University Hospital Mannheim